HomeCluesAnesthetic first used on a patient in 1842

Anesthetic first used on a patient in 1842

The New York Times crossword clue “Anesthetic first used on a patient in 1842” answer is ETHER. Below is every Crossword, Midi and Mini puzzle date it has appeared in.

ANSWER
5 lettersMost recent: September 7 2025

In the NYT Crossword

This clue appeared in the main New York Times Crossword on these dates:

About this clue

The clue “Anesthetic first used on a patient in 1842” resolves to ETHER, a 5-letter answer. In the New York Times Crossword, Midi and Mini, the same clue can be reused over the years, sometimes with a different answer — use the dates above to find the exact puzzle you are solving.

Sofia Marquez
Sofia Marquez
NYT Crossword Editor

Sofia has solved the New York Times Crossword, Midi and Mini every morning for over a decade. She personally verifies every answer on NYTSolver against the official NYT puzzle before publishing.